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Beta cells ( β-cells ), are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin. [1] Constituting ~50-70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels. [2]

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An organelle (think of it as a cell's internal organ) is a membrane bound structure found within a cell. Just like cells have membranes to hold everything in, these mini-organs are also bound in a double layer of phospholipids to insulate their little compartments within the larger cells.

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There are two main types of B-cells: plasma cells and memory cells. Both types help protect you from infection and disease. Plasma cells: Plasma cells release antibodies in response to antigens. Once a B-cell becomes a mature plasma cell, it can release up to 2,000 antibodies per second. Plasma cells are also called plasmacytes or effector cells.

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2.1 Properties of EVs. EVs, a heterogeneous family of membrane-limited vesicles originating from the endosome or plasma membrane, can be divided into three types according to size (Abels and Breakefield, 2016).Apoptotic bodies, ranging from 800 to 5,000 nm, are produced by shedding cells during apoptosis, while microvesicles with a 200-2000 diameter are produced by the plasma membrane in a.

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The Jurkat cell line is an immortalized T lymphocyte cell line that was originally obtained from the peripheral blood of a boy with T cell leukemia [14 ].

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Twenty years of investigation have yielded a detailed view of the signalling machinery engaged by T-cell receptors (TCRs). Many of the fundamental insights into TCR signalling came from studies.

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The nucleus is an organelle that contains a cell's genes. Chloroplasts are organelles that carry out photosynthesis, which makes the food plant cells need to live. This food is in the form of sugars. Plant cells have chloroplasts and a cell wall, but animal cells do not.

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The human Jurkat cell line was established from acute T cell leukemia. Jurkat cells have been extensively used in vitro to delineate the signaling pathways induced by the engagement of T-cell receptors and to study the expression of various chemokine receptors susceptible to viral entry, particularly HIV [1]. T cell activation results in the.